Primary Biliary Cholangitis (PBC) in Denver, CO

Ready to Consult a GI Physician?

Find a Provider

Primary biliary cholangitis (PBC), once called primary biliary cirrhosis, is an uncommon chronic liver disease. PBC is a chronic immune system condition that slowly damages the bile ducts (known as the intrahepatic bile ducts) in your liver. Bile aids with digesting fats and riding the body of fat, waste products, and worn-out red blood cells. This disorder may additionally lead to severe concerns in the liver. When the bile ducts become damaged or dysfunctional, bile can accumulate in your liver and result in scarring. When the liver becomes too damaged, it might lead to liver cirrhosis.

To learn more about this condition or to receive treatment for primary biliary cholangitis (PBC) in Denver, CO, we encourage you to request a consultation with us. Our Colorado Gastroenterology providers are here to offer customized treatments for individuals within the area.

Primary biliary cholangitis is an autoimmune disease. This means that the immune system mistakenly destroys healthy cells and tissues. Inflammation of the liver occurs when white blood cells, also called T cells (T lymphocytes), begin to accumulate and harm healthy cells within the liver. Inflammation in the small ducts progresses to additional parts of the liver, destroying these cells and resulting in scarring. As your liver scars more and more, it begins to function improperly, leading to cirrhosis of the liver. It is unclear what causes these white blood cells to harm other cells, although it seems to be genetic.

Factors of increased risk

A few of the risk factors connected with having primary biliary cholangitis include:

  • Being a female
  • Specific infections
  • Region (Primary biliary cholangitis is most widespread in northern Europe and North America)
  • Tobacco and other toxic chemicals
  • Being 30 – 60 years old
  • Family line (individuals are more likely to get primary biliary cholangitis if a relative has gotten it)


If you want additional information regarding PBC and the way it affects your body, reach out to a gastrointestinal specialist at Colorado Gastroenterology now.

Generally, signs of PBC are not present until five years to two decades following diagnosis. The identification of PBC normally happens while looking for other conditions. The beginning signs of PBC are tiredness, dry mouth and eyes, and itching of the skin.

Other common symptoms of PBC are:

  • High levels of cholesterol
  • Jaundice (yellowing of the skin or eyes)
  • Upper right abdominal pain
  • Brittle bones
  • Sore muscles
  • Dark and greasy stools
  • Joint discomfort
  • Darkened skin not related to UV exposure
  • Swollen feet and ankles

It is important to diagnose PBC as early as possible. If you feel you might be in danger of getting PBC due to your genetics, or a number of the above signs, our Denver, CO GI doctors can provide a solution.

Right now there is no cure for primary biliary cholangitis. Intervention works by delaying the advancement of the condition and addressing the symptoms. A number of the common therapy recommendations are:

  • Obeticholic acid (improves liver health)
  • Physical fitness
  • Cholesterol-lowering medicines (lower itching and liver inflammation)
  • Receiving a donor liver
  • Vitamin supplements
  • Ursodeoxycholic acid (helps flush bile through the liver)

The typical expected lifespan for someone with PBC after they start showing signs is a decade unless they get a liver transplant. Though there is no remedy, you can receive the treatment required to live a better life. The providers at Colorado Gastroenterology are ready to discuss the options for treatment accessible to you in Denver, CO.

Find A Provider Find A Location

If you or a loved one could be experiencing the signs or symptoms of PBC, please know that individualized support is within reach. The GI providers at Colorado Gastroenterology are pleased to provide intervention choices to assist you in handling this liver condition and acquiring improved health and quality of life. If you'd like to speak with a provider who provides care for primary biliary cholangitis in Denver, CO, we invite you to contact a location near you.

It was a great & wonderful experience, my appointment with doctor Kevin Sieja, M,D was totally awesome, I'm looking forward to my next appointment at ease. and the staff just wonderful.

M.C. Google

I’ve been seeing Dr. Sieja for a decade now and he and his staff are always professional and attentive to my needs. I highly recommend him and Colorado GI!

S.K. Google

Dr Brenner was thorough, and detailed. Very good bedside manner and follow thru!!

H.H. Google

The wait time was very short. Dr. Rufner was very attentive and I appreciated that he took the time to review my medical records prior to my first visit with him. He was honest, kind and humorous. I liked that he explained multiple different treatment options for me to choose from. I’m very impressed and happy with the care I received.

E.A. Google

Have been going to her for a number of years. Always satisfied with my visits. Informative and answers all questions.

C.F. Google

10

Total Reviews

4.9

Average Rating